HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2,3-Dihydro-2,2-dimethyl-4-benzofurancarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 18787499 | HCID 18787499 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2,3-Dihydro-2,2-dimethyl-4-benzofurancarboxylic acid | HCID 14838233 | — |
Reaction Steps
Ethyl 2,2-dimethyl-2,3-dihydro-benzofuran-4-carboxylic acid (10 g, 45 mmol) was heated to reflux with sodium hydroxide (16.3 ml of 10N, 163 mmol) in ethanol (50 ml) for 2 hr. The mixture was concentrated in vacuo, diluted with water and made acidic with 12N HCl. The precipitate was filtered and air dried (8.6 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05856529 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-0cd8d9355eed471fa25432ae82f44e2e |
| Source note | uspto-grants-1999_01 |