2,3-Dihydro-2,2-dimethyl-4-benzofurancarboxylic acid → HCID 18787456, compound

HRID 342092Notes

Reaction equation

HRID 342092 reaction equation
[CH3:1][C:2]1([CH3:14])[CH2:6][C:5]2=[C:7]([C:11](O)=[O:12])[CH:8]=[CH:9][CH:10]=[C:4]2[O:3]1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:1][C:2]1([CH3:14])[CH2:6][C:5]2=[C:7]([CH2:11][OH:12])[CH:8]=[CH:9][CH:10]=[C:4]2[O:3]1

Participants

3

Reactant 2

HCID 148382332,3-Dihydro-2,2-dimethyl-4-benzofurancarboxylic acidHCID 21226445Aluminium lithium hydride

Product 1

HCID 18787456HCID 18787456, compoundYield 93%

Procedure

2,2-Dimethyl-2,3-dihydro-benzofuran-4-carboxylic acid (8.6 g, 45 mmol) was reduced with LAH (3.41 g, 89 mmol) similar to the above procedures to give the product as a clear oil (7.35 g, 93%).

Sources & evidence

ORD record
ord-4659ea6b67ec47f3949c8820155e83bf
Source dataset
uspto-grants-1999_01
Patent number
US05856529

Reaction notes

Loading…