HCID 18787478, compound → HCID 18787473, compound

HRID 342094Notes

Reaction equation

HRID 342094 reaction equation
C([C:3]1[C:7]2=[C:8]([C:12](O)=[O:13])[CH:9]=[CH:10][CH:11]=[C:6]2[O:5][C:4]=1[CH3:15])C.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:15][C:4]1[O:5][C:6]2[C:7](=[C:8]([CH2:12][OH:13])[CH:9]=[CH:10][CH:11]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 18787478HCID 18787478, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 18787473HCID 18787473, compoundYield 78%

Procedure

Ethyl 2-methyl-benzofuran-4-carboxylic acid (5.11 g, 26.6 mmol) was reduced with LAH (2 g, 53 mmol) similar to the above procedures to give the product as a clear oil (3.34 g, 78%).

Sources & evidence

ORD record
ord-6f6726aab15a45e59b1d9970e334b475
Source dataset
uspto-grants-1999_01
Patent number
US05856529

Reaction notes

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