HCID 22941057, compound → HCID 22941054, compound

HRID 342131Notes

Reaction equation

HRID 342131 reaction equation
C([O:8][CH2:9][CH2:10][C@H:11]1[CH2:16][N:15]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[C:18]=2[CH3:24])[C:14](=[O:25])[CH2:13][N:12]1[C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])C1C=CC=CC=1.[H][H]>CO.[Pd]>[C:29]([O:28][C:26]([N:12]1[C@@H:11]([CH2:10][CH2:9][OH:8])[CH2:16][N:15]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[C:18]=2[CH3:24])[C:14](=[O:25])[CH2:13]1)=[O:27])([CH3:31])([CH3:30])[CH3:32]

Participants

5

Reactant 2

HCID 22941057HCID 22941057, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 22941054HCID 22941054, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The product from Step D was dissolved in methanol (40 mL) and 10% Pd/C was added (0.160 g). The reaction was shaken under 60 psi hydrogen overnight. The catalyst was removed by filtration, and the solvent evaporated to give the title compound.

Workup

  1. customThe catalyst was removed by filtration
  2. customthe solvent evaporated

Sources & evidence

ORD record
ord-0eb16e1b485042718670ca4b739b4e7f
Source dataset
uspto-grants-1999_01
Patent number
US05856326

Reaction notes

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