HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Toluidine → HCID 22941063, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Toluidine | HCID 7242 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | (S)-tert-butyl 1-oxohexan-2-ylcarbamate | HCID 10420833 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | HCID 22941063 | HCID 22941063 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Example 39, Step C, except using o-toluidine (0.32 mL, 3.00 mmol), 2(S)-(tert-butoxycarbonylamino)hexanal (0.538, 2.50 mmol), sodium triacetoxyborohydride (0.795 g, 3.75 mmol) in dichloroethane (10 mL) The crude product was purified by column chromatography to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05856326 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-8782a309aed94875ae01d76c6ecb8d1e |
| Source note | uspto-grants-1999_01 |