Water → HCID 131721064, compound

Participants

Reaction Steps

1.5 g (3.6 mmol) of the pentyl ester from Example 13 were dissolved in 50 ml of tetrahydrofuran, and the mixture was treated with 10 ml of 40% strength aqueous monomethylamine solution and stirred at room temperature for 16 hours. It was then treated with water, extracted with methyl tert-butyl ether, and the organic phase was washed with water, dried over sodium sulfate and concentrated in a rotary evaporator. As a residue, 1.1 g (86% yield) of the title compound remained as a yellow oil.

Provenance & Evidence