HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylallylamine → 4-[3-(4-Bromo-phenyl)-benzo[d]isoxazol-6-yloxy]-but-2-enyl-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylallylamine | HCID 69391 | — |
| Reactant | trans-1,4-Dibromo-2-butene | HCID 641245 | — |
| Reactant | (E)-6-(4-bromo-but-2-enyloxy)-3-(4-bromo-phenyl)-benzo[d]isoxazole | HCID 67598022 | — |
| Reactant | 3-(4-Bromo-phenyl)-benzo[d]isoxazol-6-ol | HCID 135490848 | — |
| Product | 4-[3-(4-Bromo-phenyl)-benzo[d]isoxazol-6-yloxy]-but-2-enyl-methyl-amine | HCID 86753523 | — |
Reaction Steps
Analogously to Example 1, from 3-(4-bromo-phenyl)-benzo[d]isoxazol-6-ol and (E)-1,4-dibromo-2-butene via (E)-6-(4-bromo-but-2-enyloxy)-3-(4-bromo-phenyl)-benzo[d]isoxazole and by reaction with N-allyl-methyl-amine there is obtained (E)-allyl-[4-[3-(4-bromo-phenyl)-benzo[d]isoxazol-6-yloxy]-but-2-enyl-methyl-amine which is converted into the fumarate, MS: m/e 412 (M30 , 1 Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05856503 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-1851fae86f134fb38abaccfbc65ba51c |
| Source note | uspto-grants-1999_01 |