HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,6-Dibromohexane → Allyl-(6-[3-(4-bromo-phenyl)-benzo[d]isoxazol-6-yloxy]-hexyl)-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,6-Dibromohexane | HCID 12368 | — |
| Reactant | N-Methylallylamine | HCID 69391 | — |
| Reactant | 6-(6-Bromo-hexyloxy)-3-(4-bromo-phenyl)-benzo[d]isoxazole | HCID 67598297 | — |
| Reactant | 3-(4-Bromo-phenyl)-benzo[d]isoxazol-6-ol | HCID 135490848 | — |
| Product | Allyl-(6-[3-(4-bromo-phenyl)-benzo[d]isoxazol-6-yloxy]-hexyl)-methyl-amine | HCID 11729939 | — |
Reaction Steps
Analogously to Example 12b, from 3-(4-bromo-phenyl)-benzo[d]isoxazol-6-ol and 1,6-dibromohexane via 6-(6-bromo-hexyloxy)-3-(4-bromo-phenyl)-benzo[d]isoxazole and by reaction with N-allyl-methyl-amine there is obtained allyl-[6-[3-(4-bromo-phenyl)-benzo[d]isoxazol-6-yloxy]-hexyl]-methyl-amine which is converted into the fumarate, MS: m/e 443 (M+H+, 1 Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05856503 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-02c1bed63ad64cb6aec438af82fee029 |
| Source note | uspto-grants-1999_01 |