HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,6-Dibromohexane → 6-[4-(6-Bromo-benzo[d]-isoxazol-3-yl)-phenoxy]-hexyl-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,6-Dibromohexane | HCID 12368 | — |
| Reactant | N-Methylallylamine | HCID 69391 | — |
| Reactant | 6-Bromo-3-[4-(6-bromo-hexyloxy)-phenyl]-benzo[d]isoxazole | HCID 67598318 | — |
| Reactant | 4-(6-Bromo-benzo[d]isoxazol-3-yl)-phenol | HCID 136365325 | — |
| Product | 6-[4-(6-Bromo-benzo[d]-isoxazol-3-yl)-phenoxy]-hexyl-methyl-amine | HCID 22446497 | — |
Reaction Steps
Analogously to Example 1, from 4-(6-bromo-benzo[d]isoxazol3-yl)-phenol and 1,6-dibromohexane via 6-bromo-3-[4-(6-bromo-hexyloxy)-phenyl]-benzo[d]isoxazole and by reaction with N-allyl-methyl-amine there is obtained allyl-[6-[4-(6-bromo-benzo[d]-isoxazol-3-yl)-phenoxy]-hexyl-methyl-amine which is converted into the fumarate, MS: m/e 442 (M+H+, 1 Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05856503 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-2e9c175a30694f62bf54fff62070ea29 |
| Source note | uspto-grants-1999_01 |