Water → HCID 70162160, compound

Participants

Reaction Conditions

Reaction Steps

The crude methyl (1RS,2RS)-2-(cyclopropyl-methylcarbamoyl)-cyclopropanecarboxylate is dissolved in 9 ml of THF and added dropwise to a boiling suspension of 1.4 g of lithium aluminium hydride in 40 ml of THF. The reaction mixture is boiled for a further 24 hrs., then cooled to 0° C. and treated with 9 ml of water, dried, filtered and concentrated. The oil obtained is dissolved in methylene chloride, dried and concentrated to give 4.2 g of (1RS,2RS)-[2-[(cylcopropyl-methyl-amino)-methyl]-cyclopropyl]methanol, MS: m/e 156 (M+H+).

Provenance & Evidence