Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34228Generated: October 25, 2026

Diisopropylethylamine → HCID 178436342, compound

https://huagongshe.com/reaction/34228

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant2-EthylpiperidineHCID 94205—
ReactantPentafluorphenol-tetramethyluronium hexafluorophosphatHCID 15840204—
Reactant6-chloro-4-(1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazolineHCID 178463504—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 178436342HCID 178436342—

Reaction Steps

Prepared analogously to Example 37a from 6-chloro-4-[1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazoline, pentafluorophenyl-tetramethyluronium-hexafluorophosphate (PFTU), diisopropylethylamine and 2-ethyl-piperidine in DMSO at ambient temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429597B2
Source datasetuspto-grants-2008_09
ORD IDord-1c7b5ec843a84edbaadde5eb87e469ef
Source noteuspto-grants-2008_09