Dicyclohexylcarbodiimide → HCID 178439113, compound

Participants

Reaction Steps

Dicyclohexylcarbodiimide in an amount of 12.9 g was suspended in 200 ml of methylene chloride and stirred. To the suspension was added dropwise a solution prepared by dissolving 10.1 g of the 4-(2-(trans-4-(4-n-propylphenyl)cyclohexyl)ethyl)benzyl alcohol mentioned above in 200 ml of methylene chloride, and stirred at room temperature for 2 hours. Crude reaction solution thus obtained was purified by a column chromatography over a silica gel, and then the solvent was distilled off under a reduced pressure to obtain 2.8 g of 4-(2-(trans-4-(4-n-propylphenyl)cyclohexyl)ethyl)benzaldehyde.

Provenance & Evidence