反应详情

To 500 ml of toluene was added 5 ml of ethanol and 8 g of pyridine, and they were stirred. Liquid mixture of 18.5 g of the (trans-4-(2-(trans-4-n-propylcyclohexyl)ethyl)cyclohexyl)benzoylchloride mentioned above and 10 ml of toluene was added dropwise thereto, and stirred under a reflux for 2 hours. After it was cooled, the reaction solution was added to 500 ml of water and extracted with 500 ml of toluene. Organic layer was washed with water and dried over anhydrous magnesium sulfate, and the solvent was distilled off under a reduced pressure to obtain 15.5 g of (trans-4-(2-(trans-4-n-propylcyclohexyl)ethyl)cyclohexyl)ethylbenzoate.

1. additionwas added dropwise
2. stirringstirred under
3. temperaturea reflux for 2 hours
4. temperatureAfter it was cooled
5. extractionextracted with 500 ml of toluene
6. washOrganic layer was washed with water
7. dry with materialdried over anhydrous magnesium sulfate
8. distillationthe solvent was distilled off under a reduced pressure