4-Ethylbenzaldehyde → HCID 4385963, compound

Participants

Reaction Steps

The same method but starting from racemic tryptophan methyl ester and 4-ethylbenzaldehyde gave the cis and trans isomer of the title compound. Cis isomer:white solid 1H NMR (CDCl3)δ(ppm):7.65-7.1 (m, 9H, H aromatic); 5.25 (brs, 1H, H-1); 4 (dd, 1H, H-3); 3.9 (s, 3H, CO2CH3); 3.4 (ddd, 1H, H-4); 3.1 (m, 1H, H-4); 2.7 (q, 2H, CH2CH3) 1.4 (t, 3H, CH2CH3). Trans isomer:white solid m.p.:187° C.

Provenance & Evidence