Hydrochloric Acid → HCID 53704353, compound

Participants

Reaction Steps

Sodium borohydride (38 mg) was added to a solution of 6-nitro-1-oxo-1,2,3,4-tetrahydrodibenzofuran (231 mg) in a mixture of ethanol (1.5 ml) and N,N-dimethylformamide (1.5 ml). The mixture was stirred at ambient temperature for 20 minutes, diluted with water and acidified with 3.6% hydrochloric acid. The separated oil was extracted with ethyl acetate and the extract was washed with aqueous saturated sodium bicarbonate and brine, dried over sodium sulfate and concentrated in vacuo. The residue was crystallized from diisopropyl ether to give 1-hydroxy-6-nitro-1,2,3,4-tetrahydrodibenzofuran (175 mg).

Provenance & Evidence