HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Methyl-7-nitro-3-phthalimidomethylbenzo[b]furan
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Reactant | 3-Chloromethyl-2-methyl-7-nitrobenzo[b]furan | HCID 70199996 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Methyl-7-nitro-3-phthalimidomethylbenzo[b]furan | HCID 70198738 | 95.7% |
Reaction Steps
A mixture of 3-chloromethyl-2-methyl-7-nitrobenzo[b]furan (410 mg) and potassium phthalimide (506 mg) in N,N-dimethylformamide (10 ml) was stirred at ambient temperature for 3 hours. Then, the mixture was poured into cold water and the separated solid was collected, washed with water and dried to give 2-methyl-7-nitro-3-phthalimidomethylbenzo[b]furan (585 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05858995 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-79d66e6abc714a059aeeef27c4a11487 |
| Source note | uspto-grants-1999_01 |