反应详情

温度

60 °C

A mixture of 7-amino-2,3-dimethylbenzo[b]furan (100 mg) and 6-chloro-N-methylisatoic anhydride (147 mg) in acetic acid (2 ml) was stirred at 60° C. for 2 hours. The reaction mixture was concentrated in vacuo and the residue was crystallized from a mixture of ethanol and water to give 2,3-dimethyl-7-(2-chloro-6-methylaminobenzoylamino)benzo[b]furan (210 mg)

1. concentrationThe reaction mixture was concentrated in vacuo
2. customthe residue was crystallized from a mixture of ethanol and water