Nitric Acid → HCID 54233480, compound

HRID 342462Notes

Reaction equation

HRID 342462 reaction equation
[N+:1]([O-:4])(O)=[O:2].[Cl:5][C:6]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:7]=1[C:8]([NH:10][C:11]1[C:19]2[O:18][C:17]3[CH2:20][CH2:21][CH2:22][CH2:23][C:16]=3[C:15]=2[CH:14]=[CH:13][CH:12]=1)=[O:9].O>C(O)(=O)C>[Cl:5][C:6]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:7]=1[C:8]([NH:10][C:11]1[C:19]2[O:18][C:17]3[CH2:20][CH2:21][CH2:22][CH2:23][C:16]=3[C:15]=2[CH:14]=[CH:13][C:12]=1[N+:1]([O-:4])=[O:2])=[O:9]

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 962WaterHCID 53735795HCID 53735795, compound

Product 1

HCID 54233480HCID 54233480, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Nitric acid (d; 1.5, 0.033 ml) was added to a solution of 6-(2,6-dichlorobenzoylamino)-1,2,3,4-tetrahydrodibenzofuran (200 mg) in acetic acid at 4° C. The mixture was stirred at ambient temperature for 5 hours and poured into cold water. The separated solid was collected and washed with isopropyl alcohol to give 6-(2,6-dichlorobenzoylamino)-7-nitro-1,2,3,4-tetrahydrodibenzofuran (17 mg).

Workup

  1. customThe separated solid was collected
  2. washwashed with isopropyl alcohol

Sources & evidence

ORD record
ord-f7b5b21299dd4fdeb6d18c2b2e502cc8
Source dataset
uspto-grants-1999_01
Patent number
US05858995

Reaction notes

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