4-(Chloromethyl)pyridine → 3-(3-chloropropyl)-5-methyl-1-pyrid-4-ylmethyl-2,4(1H,3H)-pyrimidinedione

HRID 342531Notes

Reaction equation

HRID 342531 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][N:5]1[C:10](=[O:11])[C:9]([CH3:12])=[CH:8][NH:7][C:6]1=[O:13].[N:14]1[CH:19]=[CH:18][C:17]([CH2:20]Cl)=[CH:16][CH:15]=1>>[Cl:1][CH2:2][CH2:3][CH2:4][N:5]1[C:10](=[O:11])[C:9]([CH3:12])=[CH:8][N:7]([CH2:20][C:17]2[CH:18]=[CH:19][N:14]=[CH:15][CH:16]=2)[C:6]1=[O:13]

Participants

3

Reactant 2

HCID 745714-(Chloromethyl)pyridineHCID 110418353-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

Product 1

HCID 538142743-(3-chloropropyl)-5-methyl-1-pyrid-4-ylmethyl-2,4(1H,3H)-pyrimidinedione

Procedure

substituting 3-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione and pyrid-4-ylmethyl chloride gave 3-(3-chloropropyl)-5-methyl-1-pyrid-4-ylmethyl-2,4(1H,3H)-pyrimidinedione;

Sources & evidence

ORD record
ord-47d54e7458a0478f80fde3be934f4314
Source dataset
uspto-grants-1999_01
Patent number
US05859014

Reaction notes

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