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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 342548Generated: October 31, 2026

4-Benzyl-1-(2-oxazol-2-ylphenyl)piperazine → HCID 10657035, compound

https://huagongshe.com/reaction/342548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyl-1-(2-oxazol-2-ylphenyl)piperazineHCID 10567652—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 10657035HCID 1065703573.9%

Reaction Conditions

Temperature25 °C

Reaction Steps

A mixture of the 4-benzyl-1-(2-oxazol-2-ylphenyl)piperazine (0.906 g, 2.84 mmol), obtained as in the proceeding paragraph, 10% palladium on carbon (1 g) and methanol (20 mL) was stirred 4 hours at 25° C. under a hydrogen atmosphere (15 psi). The reaction mixture then was filtered and concentrated by rotary evaporation to give 1-(2-oxazol-2-ylphenyl)piperazine (0.480 g, 2.1 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05859014
Source datasetuspto-grants-1999_01
ORD IDord-3989cfeadf294f819dec718acbec365e
Source noteuspto-grants-1999_01