HCID 53923744, compound → HCID 53810755, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of the 4-(2-nitrophenyl)piperazine-1-carbaldehyde (3.57 g, 15.2 mmol), obtained as in the proceeding paragraph, 10% palladium on carbon and ethanol (50 mL) was stirred approximately 12 hours at 25° C. under a hydrogen atmosphere (15 psi). The reaction mixture then was filtered and concentrated to give 4-(2-aminophenyl)piperazine-1-carbaldehyde (2.91 g, 14.1 mmol), m.p. 129°-133° C.

Provenance & Evidence