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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 342563Generated: October 31, 2026

1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazine → HCID 70201570, compound

https://huagongshe.com/reaction/342563

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazineHCID 10491565—
ReactantHCID 54046551HCID 54046551—
ProductHCID 70201570HCID 70201570—

Reaction Steps

substituting 1-[2-(2,2,2-trifluoroethoxy)phenyl]piperazine and 3-(3-chloropropyl)-1-benzyl-5-ethyl-2,4(1H,3H)-pyrimidinedione gave 1-benzyl-3-{3-[4-(2-(2,2,2-trifluoroethoxy)phenyl)piperazin-1-yl]propyl}-5-ethyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 180°-181° C.; Anal.: Calcd. for C28H33F3N4O3.HCl: C, 58.56; H, 6.11; N, 9.76%; Found: C, 58.83; H, 6.11; N, 9.77%;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05859014
Source datasetuspto-grants-1999_01
ORD IDord-15be9a8d44f54df48f877b4f75cd01ca
Source noteuspto-grants-1999_01