反应详情

substituting 1-[2-(2,2,2-trifluoroethoxy)phenyl]piperazine and 3-(3-chloropropyl)-1-benzyl-5,6-dimethyl-2,4(1H,3H)-pyrimidinedione gave 1-benzyl-3-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-5,6-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 221°14 222° C.; Anal.: Calcd. for C28H33F3N4O3.(HCl)1.1 : C, 58.37; H, 6.06; N, 9.72%; Found: C, 58.38; H, 5.96; N, 9.58%;