Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 342587Generated: October 31, 2026

HCID 10958012, compound → 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione

https://huagongshe.com/reaction/342587

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 10958012HCID 10958012—
Reactant3-(3-chloropropyl)-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedioneHCID 15840668—
Product3-(3-{4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedioneHCID 70202296—

Reaction Steps

substituting 1-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazine and 3-(3-chloropropyl)-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione gave 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05859014
Source datasetuspto-grants-1999_01
ORD IDord-d723a87bd348425385bff6087a22ba2c
Source noteuspto-grants-1999_01