1-(2-Chlorophenyl)piperazine → HCID 70202765, compound

HRID 342591Notes

Reaction equation

HRID 342591 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1.Cl[CH2:15][CH2:16][CH2:17][N:18]1[C:23](=[O:24])[C:22]([CH3:25])=[CH:21][N:20]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:33])([CH3:32])[CH3:31])[C:19]1=[O:34]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][N:11]([CH2:15][CH2:16][CH2:17][N:18]2[C:23](=[O:24])[C:22]([CH3:25])=[CH:21][N:20]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:32])([CH3:31])[CH3:33])[C:19]2=[O:34])[CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 4156281-(2-Chlorophenyl)piperazineHCID 702026073-(3-chloropropyl)-5-methyl-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione

Product 1

HCID 70202765HCID 70202765, compound

Procedure

substituting 1-(2-chlorophenyl)piperazine and 3-(3-chloropropyl)-5-methyl-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione gave 3-{3-[4-(2-chlorophenyl)piperazin-1-yl]propyl}-5-methyl-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione;

Sources & evidence

ORD record
ord-73feb30d3833464c9b3ebb051dc792bd
Source dataset
uspto-grants-1999_01
Patent number
US05859014

Reaction notes

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