HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10958012, compound → 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-5-fluoro-1-[2-(trimethylsilyl)ethoxymethyl)-2,4(1H,3H)-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10958012 | HCID 10958012 | — |
| Reactant | 3-(3-chloropropyl)-5-fluoro-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione | HCID 70202013 | — |
| Product | 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-5-fluoro-1-[2-(trimethylsilyl)ethoxymethyl)-2,4(1H,3H)-pyrimidinedione | HCID 70202567 | — |
Reaction Steps
substituting 1-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazine and 3-(3-chloropropyl)-5-fluoro-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione gave 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-5-fluoro-1-[2-(trimethylsilyl)ethoxymethyl)-2,4(1H,3H)-pyrimidinedione;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05859014 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-53a318d6000c43838c7a572ed2d2d7de |
| Source note | uspto-grants-1999_01 |