Benzylamine → HCID 178512309, compound

Participants

Reaction Steps

To the compound of Example 10 (400 mg, 0.79 mmol) in anhydrous tetrahydrofuran (10 ml) was added benzylamine (1 ml, excess). The mixture was stirred at room temperature for 72 h. The solvent and volatiles were removed in vacuo to yield the title compound as a white solid (300 mg). 1Hnmr (300 MHz, CDCl3) δ 3.28 (2H, d, J 7.99 Hz), 4.21 (1H, t, J 7.98 Hz), 4.47 (2H, d, J 5.69 Hz), 5.27 (1H, br), 6.43 (1H, t, J 73.58 Hz), 6.47 (1H, t, J 73.39 Hz), 6.89 (2H, d, J 6.03 Hz), 6.99-7.34 (12H, c) and 8.38 (2H, d, J 6.04 Hz). For C29H23N5O7F4 requires C, 63.94%; H, 4.47%; N, 12.43%; Found C, 63.87%; H, 4.48%; N, 12.52%.

Provenance & Evidence