4-Fluorobenzylamine → HCID 178512313, compound

Participants

Reaction Steps

From the compound of Example 10 (400 mg, 0.79 mmol) and 4-fluorobenzylamine (1 ml, excess) as a white solid (300 mg). 1Hnmr (300 MHz, CDCl3) δ 3.29 (2H, d, J 8.0 Hz), 4.23 (1H, t, J 7.99 Hz), 4.43 (2H, d, J 5.67 Hz), 5.10 (1H, br), 6.44 (1H, t, J 73.57 Hz), 6.48 (1H, t, J 73.34 Hz), 6.90 (2H, d, J 5.89 Hz), 7.02-7.06 (2H, c), 7.10 (1H, br), 7.13-7.26 (8H, c) and 8.39 (2H, d, J 5.97 Hz). m/z (ESI, 60V) 582 (MH+, 100), 562 (21), 540 (39), 489 (15), 447 (12).

Provenance & Evidence