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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34277Generated: October 29, 2026

Methyl iodide → 3-Methylthio-4-benzyl-5-[(4-methyl-1-piperazinyl)methyl]-1,2,4-triazole

https://huagongshe.com/reaction/34277

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 178480849HCID 178480849—
SolventMethanolHCID 887—
Product3-Methylthio-4-benzyl-5-[(4-methyl-1-piperazinyl)methyl]-1,2,4-triazoleHCID 20129150—

Reaction Steps

The reaction of 3-mercapto-4-benzyl-5-[(4-methyl-piperazinyl)methyl]-1,2,4-triazole prepared as in Example 1 with methyl iodide and sodium methoxide in methanol by standard techniques yields 3-methylthio-4- benzyl-5-[(4-methyl-1-piperazinyl)methyl]-1,2,4-triazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04761415
Source datasetuspto-grants-1988_08
ORD IDord-4231c277fc4e4759b8b3366eb6e0df33
Source noteuspto-grants-1988_08