HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 69823554, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl Ethyl Ketone | HCID 6569 | — |
| Reactant | 1,3-Dibromopropane | HCID 8001 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 53691952 | HCID 53691952 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 69823554 | HCID 69823554 | — |
Reaction Steps
A solution of 4-tert-butyl-7-hydroxy-8-propylcoumarin (380 mg), 1,3-dibromopropane (0.45 ml) and potassium carbonate (240 mg) in 2-butanone (15 ml) was refluxed for five hours. The mixture was partioned between 0.2N HCl and ethyl acetate, dried over magnesium sulfate and concentrated. Column Chromatography (silica gel 60, 50% methylene chloride in hexane) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05859051 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-dd74662a6247435ab67e498a2b004201 |
| Source note | uspto-grants-1999_01 |