HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Allyloxy-(2-ethyl-2-oxoethoxy)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-(Allyloxy)phenol | HCID 5314152 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Allyloxy-(2-ethyl-2-oxoethoxy)benzene | HCID 54559797 | — |
Reaction Steps
A solution of 3-allyloxyphenol (1.19 g), 2-bromoacetophenone (1.0 g) and potassium carbonate (1.10 g) in 2-butanone (15 ml) was refluxed for four hours. The mixture was partioned between 0.2N HCl and ethyl acetate. The organic layer was dried over magnesium sulfate, filtered, concentrated in vacuo. Column Chromatography (silica gel 60, 50% methylene chloride in hexane) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05859051 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-068d28c25dbf4c56bf68a52145af0b7a |
| Source note | uspto-grants-1999_01 |