HCID 67637700, compound → HCID 15391045, compound

Participants

Reaction Steps

To a solution of 5-{2-[tert-butoxycarbonyl-(2(S)-hydroxy-3-phenoxypropyl)-amino]-propyl}-1-(4-nitro-benzyl)-1H-indole-2-carboxylic acid benzyl ester (134 mg, 0.19 mmol) in THF (6 ml) was added 14 mg of 10% Pd/C catalyst. The reaction mixture was hydrogenated on a Parr shaker at 45 psi for about 4 hrs and then filtered to remove the catalyst. The filtrate was concentrated under reduced pressure to afford a yellow foam (112 mg), AP-MS 572.

Provenance & Evidence