Ethyl orthoformate → HCID 53796438, compound

Participants

Reaction Steps

A mixture of 3-cyclopropyl-1-(3,4-difluoro-2-methylsulphonylphenyl)propane-1,3-dione (0.85 g) and triethyl orthoformate (1.04 g) in acetic anhydride was stirred and heated at reflux for 4 hours. It was evaporated to dryness and the residue was treated with toluene and re-evaporated to give 3-cyclopropyl-1-(3,4-difluoro-2-methylsulphonylphenyl)-2-ethoxy methylenepropane-1,3-dione (1.13 g) as a brown oil which was not purified further.

Provenance & Evidence