Butyl bromide → HCID 15066010, compound

Participants

Reaction Conditions

Reaction Steps

The mixture of 2-hydroxy-6-naphthoic acid of 18.8 g, N,N-dimethylformamide of 150 g and anhydrous sodium carbonate of 13.3 g was heated to 70° C., and n-butyl bromide of 16.4 g was dropwise added thereto in one hour. After finishing dropwise adding, the suspension was further stirred at 70° to 80° C. for 6 hours. The reaction mixture was cooled down to room temperature and filtrated off the inorganic salt. Then the filtrate was discharged into water of 1000 g. The deposited solid was separated, and sludging was carried out in n-hexane, whereby n-butyl 2-hydroxy-6-naphthoate of 22.0 g was obtained in the form of brown crystal.

Provenance & Evidence