1-Bromo-4-iodobenzene → HCID 10714724, compound

HRID 343254Notes

Reaction equation

HRID 343254 reaction equation
[F:1][C:2]1[CH:3]=[C:4](B(O)O)[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[Br:20][C:21]1[CH:26]=[CH:25][C:24](I)=[CH:23][CH:22]=1>C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[Br:20][C:21]1[CH:26]=[CH:25][C:24]([C:4]2[CH:5]=[CH:6][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])=[C:2]([F:1])[CH:3]=2)=[CH:23][CH:22]=1

Participants

4

Reactant 2

HCID 115221-Bromo-4-iodobenzeneHCID 10611926Boronic acid, [3-fluoro-4-(octyloxy)phenyl]-

Product 1

HCID 10714724HCID 10714724, compound

Reagents, catalysts & solvents 1

HCID 178418397HCID 178418397, compoundCatalyst

Procedure

This was prepared using a similar method to that described for compound 8. Quantities: 3-fluoro-4-octoxyphenyl boronic acid (7.0 g, 0.026 mol), 4-bromoiodobenzene (5.88 g, 0.021 mol), tetrakis(triphenylphosphine)palladium (0) (0.8 g, 0.7 mol).

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-700c23135ce74c19be4a59b484c622cb
Source dataset
uspto-grants-1999_01
Patent number
US05861109

Reaction notes

Loading…