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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 343287Generated: October 30, 2026

Potassium Carbonate → Methyl 2-[5-chloro-2-[4-(4-chloro-5-difluoromethoxy-1-methylpyrazol-3-yl)phenylthiomethyl]phenoxy]propanoate

https://huagongshe.com/reaction/343287

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantMethyl 2-(2-chloromethyl-5-chlorophenoxy)propionateHCID 53768369—
Reactant4-(4-Chloro-5-difluoromethoxy-1-methylpyrazol-3-yl)thiophenolHCID 135960884—
SolventDimethylformamideHCID 6228—
ProductMethyl 2-[5-chloro-2-[4-(4-chloro-5-difluoromethoxy-1-methylpyrazol-3-yl)phenylthiomethyl]phenoxy]propanoateHCID 67703361—

Reaction Steps

This compound is prepared in a manner analogous to that of Step I of Example 1, using 0.58 gram (0.002 mole) of 4-(4-chloro-5-difluoromethoxy-1-methylpyrazol-3-yl)thiophenol, 0.32 gram (0.002 mole) of methyl 2-(5-chloro-2-chloromethylphenoxy)propanoate (prepared as in Steps A through D of Example 2), and 0.41 gram (0.003 mole) of potassium carbonate in 60 mil of N,N-di-methylformamide, yielding the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05861359
Source datasetuspto-grants-1999_01
ORD IDord-9a7c099280614c60a3dab91b2277e432
Source noteuspto-grants-1999_01