HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylsilyl cyanide → 4-Bromo-2-cyanopyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylsilyl cyanide | HCID 82115 | — |
| Reactant | 4-Bromopyridin-1-ium-1-olate | HCID 139708 | — |
| Product | 4-Bromo-2-cyanopyridine | HCID 693283 | — |
Reaction Steps
The title compound was prepared from 4-bromo-pyridine-1-oxide (Rec. Trav. chime, 1951, 70, 581) and trimethylsilyl cyanide, using the procedure described in Chem. Pharm. Bull., 1985, 33, 565, and obtained as a solid (49% yield), m.p. 88°-93° C. Rf 0.53 (SS 11). Found: C,39.15; H,1.50; N,15.07. C6H3BrN2 requires C,39.37; H,1.65; N,15.30%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05861393 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-2b6e3232d8d6463cb659dfe0d57906c0 |
| Source note | uspto-grants-1999_01 |