HCID 67582419, compound → HCID 67583446, compound

HRID 343350Notes

Reaction equation

HRID 343350 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7](/[CH:11]=[CH:12]/[C:13]3[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=3)=[CH:8][CH:9]=2)[CH:4]=[CH:3]1>CO>[CH2:4]([N:16]1[CH2:17][CH:18]=[C:13](/[CH:12]=[CH:11]/[C:7]2[CH:6]=[C:5]3[C:10](=[CH:9][CH:8]=2)[N:2]([CH3:1])[CH:3]=[CH:4]3)[CH2:14][CH2:15]1)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

3

Reactant 1

HCID 67582419HCID 67582419, compound

Product 1

HCID 67583446HCID 67583446, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound was prepared from (E)-4-(1-methylindol-5-yl)ethenylpyridine by an analogous procedure to Example 1, m.p. 137.5°-138.5° C. (MeOH); (Found: C, 84.17; H, 7.11; N, 8.48. C23H24N2 requires C, 84.11; H, 7.37; N, 8.53%); δH (CDCl3) 2.45 (2H, br s, tetrahydropyridinyl CH2), 2.68 (2H, m, tetrahydropyridinyl CH2), 3.13 (2H, br s, tetrahydropyridinyl CH2), 3.63 (2H, s, PhCH2N), 3.77 (3H, s, N-CH3), 5.77 (1H, br s, tetrahydropyridinyl CH), 6.43 (1H, m, 3'-H), 6.58 (1H, d, J 16.1 Hz, CH=CHAr), 6.77 (1H, d, J 16.1 Hz, CH=CHAr), 7.00 (1H, d, J 3.1 Hz, 2'-H), 7.23-7.39 (7H, m, ArH), and 7.61 (1H, s, ArH); m/z (ES+) 329 (+1)+.

Sources & evidence

ORD record
ord-adcfcfd270744baf80917ff9a57e9984
Source dataset
uspto-grants-1999_01
Patent number
US05861407

Reaction notes

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