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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 343413Generated: October 29, 2026

HCID 178451206, compound → HCID 178451207, compound

https://huagongshe.com/reaction/343413

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178451206HCID 178451206—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 178451207HCID 17845120795%

Reaction Steps

A solution of 4-{2-[3-(1-tert-butoxycarbonylmethyl-piperidin-4-yl)-1H-indazol-6-yl]-(E)-vinyl}-piperidine-1-carboxylic acid tert-butyl ester (0.84 g, 1.60 mmol) in ethanol (80 ml) was hydrogenated over palladium on carbon (10%, 0.14 g) for 4 h. The catalyst was filtered off and the filtrate was evaporated in vacuo to give the title compound as an ivory solid (0.80 g, 95%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05861414
Source datasetuspto-grants-1999_01
ORD IDord-37c96852e653488da014d682f539de29
Source noteuspto-grants-1999_01