HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178451206, compound → HCID 178451207, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178451206 | HCID 178451206 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178451207 | HCID 178451207 | 95% |
Reaction Steps
A solution of 4-{2-[3-(1-tert-butoxycarbonylmethyl-piperidin-4-yl)-1H-indazol-6-yl]-(E)-vinyl}-piperidine-1-carboxylic acid tert-butyl ester (0.84 g, 1.60 mmol) in ethanol (80 ml) was hydrogenated over palladium on carbon (10%, 0.14 g) for 4 h. The catalyst was filtered off and the filtrate was evaporated in vacuo to give the title compound as an ivory solid (0.80 g, 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05861414 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-37c96852e653488da014d682f539de29 |
| Source note | uspto-grants-1999_01 |