HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[2-(3,4-Dichlorophenyl)-4-oxobutyl]-N-methylbenzamide → N-Methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[2-(3,4-Dichlorophenyl)-4-oxobutyl]-N-methylbenzamide | HCID 22137499 | — |
| Reactant | 4-[(2,2,2-Trifluoroacetyl)[2-(2,2,2-trifluoroacetylamino)ethyl]amino]piperidine | HCID 22137541 | — |
| Reactant | (S)-N-[2-(3,4-Dichlorophenyl)-4-[4-[(2,2,2-trifluoro-acetyl)[2-(2,2,2-trifluoroacetylamino)ethyl]amino]piperidino]-butyl]-N-methylbenzamide | HCID 54511194 | — |
| Product | N-Methylbenzamide | HCID 11954 | — |
Reaction Steps
(S)-N-[2-(3,4-Dichlorophenyl)-4-[4-[(2,2,2-trifluoroacetyl)[2-(2,2,2-trifluoroacetylamino)ethyl]amino]piperidino]-butyl]-N-methylbenzamide. Using the procedure of Example 1, replacing 4-(2-oxo-1,3-oxazolidin-3-yl)piperidine with 4-[(2,2,2-trifluoroacetyl)[2-(2,2,2-trifluoroacetylamino)ethyl]amino]piperidine, and N-[-2-(3,4-dichlorophenyl)-4-oxobutyl]-N-methylbenzamide with the (S)-enantiomer, the N-methylbenzamide was obtained as a viscous oil; MS: m/z=669(M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05861392 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-45c91469529a4707a02864e3e6816034 |
| Source note | uspto-grants-1999_01 |