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Triethylamine → 3-(2-Ethylphenyl)-isopropyl-2-thioxo-imidazolidin-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | NoName_76 | HCID 414244 | — |
| 反応物 | 2-Ethylphenyl isothiocyanate | HCID 2796213 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 3-(2-Ethylphenyl)-isopropyl-2-thioxo-imidazolidin-4-one | HCID 85701534 | 26% |
反応手順
The title compound was prepared by the procedure described in Example 18 using 16.3 g of 2-ethylphenyl-isothiocyanate, 21.2 g of N-isopropyl glycine, 21.0 g of triethyl amine, and 300 mL of chloroform. Crystallization from diethyl ether afforded the title compound (6.8 g) as a white solid, m.p. 103°-105° C. Anal. Calcd. for. C14H18N2OS: C, 64.09; H, 6.92; N, 10.68. Found: C, 64.08; H, 6.92; N, 10.62. Mass spectrum (EI, M.+) m/z 262.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05861517 |
| 出典データセット | uspto-grants-1999_01 |
| ORD ID | ord-8ba271c0a41747f5a8261f2957fe13f9 |
| 出典メモ | uspto-grants-1999_01 |