HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidine-4-carboxamide monohydrochloride → 1-[2-[3-(2-Fluoro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl]-4-phenyl-piperidine-4-carboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidine-4-carboxamide monohydrochloride | HCID 3017129 | — |
| Reactant | 2-[3-(2-Fluoro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate | HCID 86750923 | — |
| Product | 1-[2-[3-(2-Fluoro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl]-4-phenyl-piperidine-4-carboxylic acid amide | HCID 54313537 | — |
Reaction Steps
Prepare by the method of example 3.3 using 2-[3-(2-fluoro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate (8 mmol) and 4-phenyl-piperidine-4-carboxylic acid amide hydrochloride (12 mmol). Chromatograph on silica gel to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05861416 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-08aed1fef1214a86a316e45ee158776b |
| Source note | uspto-grants-1999_01 |