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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 343755Generated: October 25, 2026

(+-)-Homocysteine → Captopril

https://huagongshe.com/reaction/343755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-HomocysteineHCID 778—
ReactantMethylene blue cationHCID 4139—
ReactantL-(+)-CysteineHCID 5862—
ReactantN-Acetyl-L-CysteineHCID 12035—
ReactantGlutathioneHCID 124886—
ProductCaptoprilHCID 44093—

Reaction Steps

Glutathione, L-cysteine, DL-homocysteine, D-penicillin, hemoglobin (bovine), methylene blue and Medium 199 sets were purchased from Sigma Chemical Co., St. Louis, Mo. N-acetylcysteine was obtained from Aldrich Chemical Co., Milwaukee, Wis. Captopril was kindly provided by Dr. Victor Dzau. Sodium nitrite, histamine and methacholine were purchased from Fisher Scientific, Fairlawn, N.J. Leukotriene D4 was purchased from Anaquest, BOC Inc., Madison, Wis. Antibiotic/antimycotic m nxture (10,000 U/ml penicillin G sodium, 10,000 mg/ml, streptomycin sulfate, 25 mg/ml amphotericin B) was purchased from Gibco laboratories, Grand Island, N.Y. Radioimmunoassay kits for the determination of cyclic GMP were purchased from New England Nuclear, Boston, Mass.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05863890
Source datasetuspto-grants-1999_01
ORD IDord-ffc0632c2edc45a1a0321463df13216b
Source noteuspto-grants-1999_01