Sulfuric Acid → HCID 178470652, compound

HRID 343765Notes

Reaction equation

HRID 343765 reaction equation
[C-:1]1([CH2:6][C:7]([OH:9])=[O:8])[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH-:10]1[CH:14]=[CH:13][CH:12]=[CH:11]1.[Fe+2:15].S(=O)(=O)(O)O>C(O)C>[C-:1]1([CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH-:10]1[CH:14]=[CH:13][CH:12]=[CH:11]1.[Fe+2:15]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 157685011287-16-7

Product 1

HCID 178470652HCID 178470652, compoundYield 199%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.00 g (8.2 mmol) of ferrocenylacetic acid are dissolved in 50 ml of ethanol. 0.5 ml of concentrated sulfuric acid is added. The mixture is brought to reflux for 1 hour. After cooling, the reaction mixture is poured into 100 ml of ice-cold water. The product is extracted with 3 times 40 ml of ether. The ethereal phase is first washed with water (2 times 40 ml) and then dried over magnesium sulfate, filtered and evaporated. 2.22 g of ethyl ferrocenylacetate are obtained. The yield of the reaction is 100%.

Workup

  1. temperatureto reflux for 1 hour
  2. temperatureAfter cooling
  3. extractionThe product is extracted with 3 times 40 ml of ether
  4. washThe ethereal phase is first washed with water (2 times 40 ml)
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. customevaporated

Sources & evidence

ORD record
ord-32d3a11f5e074a278f3052e54e84f46a
Source dataset
uspto-grants-1999_01
Patent number
US05863911

Reaction notes

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