Hydrochloric Acid → HCID 10512659, compound

Participants

Reaction Steps

A mixture of 1,2-diamino-4-chloro-5-methylbenzene hydrochloride [J Chem Soc, 117, 784 (1920)] (1.90 g, 9.84 mmol), oxalic acid (1.24 g, 13.8 mmol) and 4M hydrochloric acid (49 ml) was heated at reflux for 4.5 hours. After cooling the solid precipitate was collected by filtration, washed well with water and dried under reduced pressure at 80° C. to afford 1,4-dihydro-6-chloro-7-methylquinoxalin-2,3-dione (1.68 g, 81%) as a dark grey solid, mp>330° C.

Provenance & Evidence