Ethanol → Ethyl 3-(2,3-dimethoxyphenyl)propanoate

Participants

Reaction Steps

A mixture of (20 g, 0.0961 mole) of 2,3-dimethoxycinnannic acid in 120 mL of CHCl3 and 200 mL of EtOH was hydrogenated at 30 psig in the presence of 2.0 g of 10% Pd/C catalyst to form ethyl-3-(2,3-dimethoxy-phenyl)propionate (hereinafter, "Compound 1"). The catalyst was removed by filtration and the filtrate was evaporated under reduced pressure. The residue was distillated under reduced pressure to give 22 g (96% yield) of liquid with a boiling point of 143° C./1.15 mmHg. Elemental analysis gave C13H18O4 (C,H,N).

Provenance & Evidence