2-[(2,6-Dichloro-3-methylphenyl)amino]benzaldehyde → 1-{2-[(2,6-Dichloro-3-methylphenyl)amino]phenyl}ethanol

HRID 343888Notes

Reaction equation

HRID 343888 reaction equation
[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[C:4]([Cl:9])[C:3]=1[NH:10][C:11]1[CH:18]=[CH:17][CH:16]=[CH:15][C:12]=1[CH:13]=[O:14].[CH3:19][Mg]Br>>[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[C:4]([Cl:9])[C:3]=1[NH:10][C:11]1[CH:18]=[CH:17][CH:16]=[CH:15][C:12]=1[CH:13]([OH:14])[CH3:19]

Participants

3

Reactant 2

HCID 150273772-[(2,6-Dichloro-3-methylphenyl)amino]benzaldehydeHCID 178418573HCID 178418573, compound

Product 1

HCID 675606441-{2-[(2,6-Dichloro-3-methylphenyl)amino]phenyl}ethanol

Procedure

The desired compound is prepared by reaction of 2-[(2,6-dichloro-3-methylphenyl)amino]benzaldehyde, prepared as in step 1, with methylmagnesium bromide.

Sources & evidence

ORD record
ord-420732ad6f3e408ebf904456abb9a965
Source dataset
uspto-grants-1999_01
Patent number
US05863946

Reaction notes

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