HCID 70075262, compound → HCID 70075092, compound

HRID 343942Notes

Reaction equation

HRID 343942 reaction equation
[CH3:1][C:2]1[C:7]([O:8]CC2C=CC=CC=2)=[CH:6][C:5]([O:16]CC2C=CC=CC=2)=[CH:4][C:3]=1[CH:24]1[NH:28][C:27](=[O:29])[NH:26][C:25]1=[O:30]>CO.[Pd]>[CH3:1][C:2]1[C:7]([OH:8])=[CH:6][C:5]([OH:16])=[CH:4][C:3]=1[CH:24]1[NH:28][C:27](=[O:29])[NH:26][C:25]1=[O:30]

Participants

4

Reactant 1

HCID 70075262HCID 70075262, compound

Product 1

HCID 70075092HCID 70075092, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of 5-(2-methyl-3,5-dibenzyloxyphenyl)-hydantoin (1.13 g, 2.8 mmol) in methanol (100 ml) was shaken in a Parr hydrogenation apparatus at 60 p.s.i. over 10% Palladium/charcoal (120 mg) for 6 hours. The reaction suspension was filtered over celite and the filtrate evaporated in vacuo to give 5-(2-methyl-3,5-dihydroxyphenyl)-hydantoin as an off-white solid.

Workup

  1. filtrationThe reaction suspension was filtered over celite
  2. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-9962c805705b4a2c9c6bff0c4c3494ca
Source dataset
uspto-grants-1999_01
Patent number
US05863947

Reaction notes

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