反应详情

To a mixture of 4.9 g (47 mmol) of thiocarbohydrazide and 15 g (47 mmol) of 4-(dodecylsulfonyl)butanoic acid in 30 ml of toluene was added 0.8 g (4.7 mmol) of 3-nitrobenzeneboronic acid. The mixture was heated at reflux for 24 hr. Upon cooling, the thick precipitate was collected, rinsed with a small amount of acetonitrile (10 ml), dried in vacuo to yield 16 g (87.4%) of the desired product as a white solid. All of the analytical data confirmed the assigned structure.

1. temperatureThe mixture was heated
2. temperatureat reflux for 24 hr
3. temperatureUpon cooling
4. customthe thick precipitate was collected
5. washrinsed with a small amount of acetonitrile (10 ml)
6. customdried in vacuo