Water → HCID 44380045, compound

Participants

Reaction Conditions

Reaction Steps

Mono-nitro 1,8-diacetylanthraquinone (1 g; M.W. 397; 2.52 mmoles) was added to 10 ml of a mixture tetrahydrofuran: water=20:80 by volume. The mixture was heated to 50° C. under constant stirring followed by addition of NaCN (1.4 g; M.W. 49; 28.57 moles). The reaction mixture was maintained overnight at 50° C. under constant agitation. The resulting mixture was filtered and washed with water. The bright yellow-greenish crystals were dried at 50° C. 3-carboxy-1,8-diacetylanthraquinone was obtained in a 44% yield.

Provenance & Evidence